Back to table

Evolutionary Coupling Analysis

Predicted and experimental contacts

Interactive contact map

Secondary structure from ECs

Known pdb structures

pdb chain
2ys9 A

EC score distribution and threshold

Top ECs

Rank Residue 1 Amino acid 1 Residue 2 Amino acid 2 EC score
1 470 W 506 P 1.47
2 467 E 502 R 1.42
3 469 Y 480 D 1.40
4 483 Q 487 A 1.24
5 481 I 492 T 1.17
6 465 P 487 A 1.13
7 497 D 501 S 1.10
8 458 P 490 L 1.08
9 481 I 496 L 1.04
10 473 H 480 D 0.95
11 485 S 495 V 0.94
12 506 P 510 V 0.82
13 484 L 495 V 0.82
14 514 D 518 E 0.80
15 469 Y 473 H 0.80
16 443 R 447 E 0.75
17 458 P 494 Q 0.75
18 482 P 486 Q 0.74
19 464 Q 468 R 0.73
20 490 L 494 Q 0.72
21 474 Q 506 P 0.68
22 500 D 504 P 0.67
23 482 P 492 T 0.67
24 465 P 488 S 0.66
25 515 E 519 E 0.65
26 470 W 502 R 0.63
27 444 S 448 R 0.63
28 476 L 499 F 0.63
29 460 P 464 Q 0.63
30 443 R 448 R 0.62
31 478 E 482 P 0.60
32 469 Y 484 L 0.59
33 458 P 475 Q 0.58
34 465 P 484 L 0.58
35 513 L 517 E 0.54
36 468 R 472 A 0.53
37 454 L 460 P 0.53
38 501 S 505 Q 0.53
39 502 R 506 P 0.53
40 499 F 503 L 0.53

Alignment robustness analysis

First most common residue correlation

Second most common residue correlation

Robustness